It wasn’t a good day at Lucas Oil Stadium as Derrick Henry rumbled for 178 yards and three touchdowns as the Titans crushed the Colts 45-26 to take control in the AFC South. Ryan Tannehill threw for 221 yards and a TD while also running in for a score for the Titans, who move a game ahead of the Colts for the division lead at 8-and-3. A.J. Brown had four catches for 98 yards and a touchdown in the victory. Philip Rivers threw for 295 yards, two TD’s and an interception for the Colts, who had won their previous two including a 34-17 victory at Tennessee in Week 10. Jacoby Brissett had two rushing scores in the setback. Indy fell to 7-and-4.